Suggested Level of Knowlege: Good

LOs

BT_PO 1.115 Describe blood groups and methods of cross matching blood

BT_RT 1.7 Describe blood groups and the physiological basis of transfusion reactions

BT_PO 1.116 Outline the composition, indications and risks of use of the following blood components and products:

· Packed red cells

· Fresh frozen plasma

· Cryoprecipitate

· Platelets

· Factor VIIa

BT_PO 1.117 Describe the changes that occur during blood storage and their clinical implications

BT_RT 1.8 Outline the changes that occur in stored blood

BT_RT 1.9 Describe physiological consequences of massive transfusion

Past SAQs

2016.2, 2012.1, 2007.2 Outline the physiology of blood groupings that allows O negative packed cells to be safely transfused to most patients.

2014.2, 2010.1, 2002.2 Briefly explain the changes that occur in stored whole blood.

2005.2, 2000.2 Outline the principles of compatibility testing of blood for transfusion.

2004.1 What is 2,3 DPG? How is it produced in the red blood cells and how does it interact with haemoglobin? What is its relevance in altitude exposure, anaemia and stored blood?

References

Transfusion Physiology