Suggested Level of Knowlege: Detailed

LOs

BT_PM 1.3 Describe the basic physiological mechanisms of pain including:

· Peripheral nociception

· Conduction

· Spinal cord modulation

· Central processing of pain

· Mediators, pathways and reflexes

· Peripheral and central sensitisation

· Pre-emptive and preventive analgesia

BT_PM 1.4 Describe the physiological mechanism of progression from acute to chronic pain

BT_PM 1.5 Describe the injury response to acute pain

BT_PM 1.6 Describe the applied physiology and psychology of neuropathic pain

BT_PM 1.7 Outline the effects of pain and analgesia on injury-induced organ dysfunction

BT_PM 1.8 Describe the alterations to physiology and perception of pain in the older patient

BT_PM 1.23 Describe the prostaglandin pathways and their physiological role in the production of pain

BT_PM 1.26 Describe the location and role of NMDA receptors

BT_PO 1.89 Outline the role of prostaglandins and other autocoids

BT_RA 1.7 Describe the pain and sensory pathways

BT_RT 1.5 Describe the systemic inflammatory response and its physiological effects

Past SAQs

2016.1 Outline the physiological mechanisms of progression from acute to chronic pain and how drugs may alter this progression.

2014.2 Describe the physiology of the pain pathways and how drugs may modulate the perception of pain.

2014.1 Describe the alterations to the physiology of the nervous system in the older patient and outline the consequent effects on pain perception.

2008.1 Describe the pathways whereby myocardial ischaemia may be experienced as pain in the throat or arm regions.

2003.2 Briefly describe the NMDA (N-methyl d-aspartate) receptor and its physiological role in the central nervous system.

Pain Physiology