Suggested Level of Knowlege: Good

LOs

IT_GS 1.1 Outline the basic pharmacology of sedative/hypnotic agents (propofol, thiopentone, midazolam, ketamine), inhalational agents, opioids, muscle relaxants, reversal drugs and anti- emetic agents relevant to their clinical practice.

BT_GS 1.44 Describe the clinical pharmacology of dopamine antagonists, anti-cholinergic agents, serotonin antagonists, anti- histamines pro-kinetics and steroids relevant to premedication and the management of nausea and vomiting

BT_GS 1.62 Discuss the prevention and management of postoperative nausea and vomiting

BT_PO 1.100 Outline the pharmacology of histamine antagonists

BT_PO 1.101 Outline the pharmacology of drugs acting via effects on serotonin or serotonin receptors

BT_PO 1.102 Discuss the clinical features and management of serotonin syndrome

Past SAQs

2016.2 Briefly describe the pharmacodynamics of agents used in the treatment of post-operative nausea and vomiting (PONV), with particular reference to their site of action and side effects.

2015.2 Describe the sites of action of antiemetic agents used for post operative nausea and vomiting.

2009.2 Discuss classes of drugs that influence Post-Operative Nausea and Vomiting (PONV) including mechanisms where known.

2009.1 Outline the types of serotonin (5-hydroxytryptamine) receptors. Discuss the pharmacological agents that act at these sites.

2008.1 Classify drugs that alter activity at serotonin receptors with examples. Describe their mechanisms of action and clinical indications.

2005.2 Describe the therapeutic and unwanted effects of dexamethasone.

2005.2 Briefly outline the pharmacology of droperidol, emphasising its mechanism of action, perioperative use and side effects.

2005.1 Classify anti-emetic drugs. Give examples and describe side effects of each class.

References

Antiemetics